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OKC contributions to bioscience

For more than two decades, Oklahoma’s bioscience industry has grown and developed into an internationally-recognized sector. Throughout the state, pockets of research excellence continue to develop. Oklahoma’s bioscience industry encompasses a wide range of research and business focuses, with significant public and private support.

  • An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn’s disease, and colon cancer.

  • Otologic Pharmaceutics Inc. (OPI), recently entered into an exclusive license agreement with The Hough Ear Institute. The technology is expected to be ready for human clinical trials in 2017. Noise-induced hearing loss is the single largest addressable cause of hearing loss problems. Hearing loss costs the US up to $56 billion per year in lost productivity, retraining and health care for the hard of hearing. Currently, no pharmaceutical treatments for hearing loss are available to patients. OPI has received a contract from the Naval Medical Logistics Command (NMLC) to further their research.

  • Courtney Houchen and his colleagues at Oklahoma City-based COARE Biotechnology are accelerating a new technology to market that shows promise in fighting pancreatic cancer and other solid-tumor cancers. COARE Biotechnology is developing biomarker panels for the detection of oncogenic proteins and monoclonal antibodies against key stem cell signaling molecules expressed in tumor initiating cells.

  • Researchers at Moleculera Labs have discovered evidence that points to a relationship between certain bacterial infections and autoimmune attacks that can disrupt normal neurologic functioning. Using a panel of biomarker tests for autoantibodies can help physicians better diagnose and treat the underlying cause of these conditions, which are often misdiagnosed and treated inappropriately with psychotropic drugs.

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